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Nature slapped both theories of consciousness in the face at the same time

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2023

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A world-class neuroscientist has lost a 25-year-old gamble

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The bet is a case of wine

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It's one of the deepest mysteries of mankind.

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Where does consciousness live in the brain?

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His name is Christopher Koch

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I used to believe that within 25 years, science would find a neural marker of consciousness.

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What happened?

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He was at the Science of Consciousness Annual Meeting in 2023

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Handed philosopher David Chalmers a bottle of 1978 Madeira

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Admit with a wry smile

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Things were not as clear as he had imagined

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Chalmers takes the drink

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He smiled and said something

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It is clear that

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Things are not clear

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Hello

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Hello.

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I am Wang Lijie

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But the story doesn't end there.

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The year Koch lost the bet

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One of the largest consciousness experiments in history

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It is being promoted simultaneously in multiple laboratories around the world

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This project is called COGITATE.

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Funded by Templeton World Charitable Foundation

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It took seven years.

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2025

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The results are finally out

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Posted directly in Nature

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This paper does something unprecedented

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It brings together two theories that have dominated the science of consciousness for decades

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Pull into the same ring

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Use the same set of experiments to judge simultaneously

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What happened?

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Both theories have been substantially challenged

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In vernacular

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Both overturned

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Today's video

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I'm going to tell you the story of this paper.

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But what I'd rather explore

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Is a bigger problem behind this result

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Why haven't we been able to find the switch on consciousness?

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This failure itself

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Are they telling us something profound?

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Let's first understand these two theories

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The first is called integrated information theory.

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English abbreviation IIT

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It's by Giulio Tononi at the University of Wisconsin-Madison.

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The central proposition of this theory is very bold

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It says consciousness is not a function of a certain area of the brain

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It's a system's ability to integrate information itself.

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Tononi even invented a mathematical symbol to measure it

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It's called φ.

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The higher the φ value of a system

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The greater the degree of information integration

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The richer the conscious experience

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According to IIT

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The central base of consciousness is in the back of the brain

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That's the posterior cortex.

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Why the back?

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Because the posterior cortex contains a large number of densely interconnected neural circuits

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The information is highly integrated there.

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Forming a complex causal structure

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IIT forecast

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And it's this continuous synchronized activity in the posterior cortex.

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Constitutes the consciousness you are experiencing right now

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The second theory is called the global neural workspace theory

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English abbreviation GNWT

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The concept was first proposed by Bernard Barthes

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Later, the French neuroscientist Stanislas Dea

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Na developed it into a complete neuroscience model

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Its core idea is

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And consciousness is a sort of theater spotlight.

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The sensory areas in the back of the brain are always processing input.

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But most of it runs silently in the background

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You don't even realize it.

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Only when something is powerful enough to be pushed to the global stage

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Broadcast throughout the brain

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In particular, the prefrontal cortex participates in the global workspace

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You will really realize it

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The GNWT has a landmark prediction.

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It's called ignition.

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What do you mean?

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The moment you become truly aware of something

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There's a sudden burst of neural activity in the prefrontal cortex.

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It's like a match being polished.

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And this ignition occurs roughly 200 to 300 milliseconds after the stimulus is present.

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Before ignition

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And yet information just goes round and round in those sensory areas in the back of the brain.

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After ignition

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Information was thrust onto the global stage.

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You really see it

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Did you notice?

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There's a very central disagreement between these two theories.

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Does consciousness live in the front or the back of the brain?

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IIT says behind

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And that posterior cortical integration activity is consciousness itself.

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GNWT says it's up front.

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Ignition broadcasts without prefrontal lobes

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There's no real conscious experience.

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This is not philosophers arguing on the sofa.

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This is a scientific disagreement that experiments can judge

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But for decades

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Each side does its own experiment

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Cite their own evidence

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No one can convince anyone

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The experimental design you did was good for your theory

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The experimental design I did was favorable to my theory

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This phenomenon is called confirmation bias in the philosophy of science

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How do we break this deadlock?

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Someone came up with a genius solution

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It's called adversarial collaboration.

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Simply put

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Bring proponents of both theories to the same table

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Plus a bunch of neutral referee scientists

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Let's design experiments together

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Each side writes down their own predictions

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If the result is A.

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Explain that my theory is correct

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If the result is B.

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It means I was wrong.

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We then pre-register all of those predictions.

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lock

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No post-mortem modification allowed

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Finally, a neutral third party performs experiments and analyzes the data

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The essence of this approach lies in

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No one can make up a story after seeing the results

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That's what the COGITATE Alliance does.

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They recruited 256 subjects

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And they're using three state-of-the-art brain imaging technologies.

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functional magnetic resonance fMRI

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You're looking at blood flow patterns.

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High spatial accuracy

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Magnetoencephalography MEG

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It's the magnetic field.

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High time accuracy

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And intracranial electroencephalogram iEEG

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This is putting electrodes directly into the brain to measure

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What's the concept?

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This kind of data can only be collected incidentally during surgical monitoring of patients with epilepsy

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Extremely precious

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Three tools are available at the same time

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Simultaneous locking of brain activity in three dimensions: space, time and depth

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The precision and scale of this experiment are unprecedented in the history of consciousness science

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How do you do that?

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Show subjects different types of visual stimuli

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Such as faces, objects, letters

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The length of each rendering is different

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Half a second, a second, a second and a half.

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And then we used all three of these tools to measure simultaneously in different areas of the brain.

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Activity patterns at different points in time

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Here it is.

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Look at IIT first

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IIT forecast

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When you become aware of a visual stimulus

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There should be sustained synchronized activity in the posterior cortex.

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That is to say

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Those circuits in the back should be tightly integrated.

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And this synchronization should continue until the stimulus wears off.

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What did the experiment find?

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The posterior cortex does have a sustained response

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Activity in the occipital and lateral temporal lobes does indeed reflect the duration of the stimulation

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But the kind of continuous synchronization within the posterior cortex predicted by IIT

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Did not appear

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There is indeed information in the back.

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But there is no IIT maintained between those regions.

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The kind of tightly interconnected model required

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This directly undermines the core proposition of IIT

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The structure of neural networks determines consciousness

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And look at GNWT.

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GNWT predicts two things

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first

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When the stimulus wears off

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The frontal lobes should have a clear ignition.

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second

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The prefrontal lobe should be able to represent the full range of visual content that you're aware of in every dimension.

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For example, what category and orientation do you see?

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What happened?

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The first prediction basically failed.

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Prefrontal lobe ignition when stimulation disappears

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Did not appear under most experimental conditions

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The second prediction was also discounted

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You do have content-specific activity in the frontal lobes.

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It can tell whether you're looking at faces or letters.

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But for such details

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The frontal lobes can do almost nothing.

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This is far from the comprehensive global broadcast that GNWT describes

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So you see

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Experiments give partial marks to both theories

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But it also deducts the most crucial points

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IIT says consciousness is back-synced.

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Experiments say that synchronization doesn't exist

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GNWT says the front of consciousness ignites.

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Experiments show that the ignition is often absent

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It's a lose-lose situation.

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And notice

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The paper also points out a sentence in particular

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These challenges are not limited to IIT and GNWT.

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They also extend to other theories of consciousness that share similar predictions

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What do you mean?

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So the shockwave didn't just hit two contestants.

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All the theories that bet big on posterior cortical synchronization or prefrontal ignition

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Have to reassess their foundation

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But I want you to stop.

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Don't jump to the conclusion that these theories are rubbish

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Because this is precisely what makes science most fascinating

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Think about it.

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Newtonian mechanics was also overturned

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But is Newtonian mechanics rubbish?

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Not at all.

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It's still surprisingly accurate on an everyday scale

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Einstein's general theory of relativity overturned Newton's absolute view of spacetime

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But Einstein's theory itself is not fully compatible with quantum mechanics to this day

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The deepest cracks in physics have yet to be repaired

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So you're saying physics failed?

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Nope.

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Every time an elaborate theory falls apart in front of an experiment

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Light leaking from cracks

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Often the next breakthrough

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And you look at the results.

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Will find a very interesting pattern

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Consciousness is indeed in the visual cortex.

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Ventral temporal lobe and inferior frontal cortex were found

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And the prefrontal and early visual areas

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There is indeed content-specific synchronization.

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That is to say

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Consciousness doesn't live in the front, it doesn't live in the back.

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It's more of a back-to-front, front-to-back dynamic.

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The actual data is far more complex than any theory can draw

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Interestingly, 2024

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There was also a review paper co-authored by multiple proponents of the theory of consciousness

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Published in Neuron, the top journal of neuroscience

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This paper acknowledges an important fact

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Current theories of consciousness

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Including IIT, GNWT, higher-order theory

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Cyclic processing theory and predictive processing theory

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The controversy between them far outweighs the consensus

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Even the most basic questions

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What is consciousness and how to identify conscious states

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What are the requirements for a qualified theory of consciousness?

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No one agreed

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What does that mean?

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Means the current state of the science of consciousness

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This is a little bit like physics a hundred years ago.

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Classical physics thought it was finishing the puzzle of the universe.

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Only two small dark clouds remain

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It turned out that those two dark clouds exploded relativity theory and quantum mechanics

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It directly overturned the entire foundation

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The science of consciousness may now be standing at a similar crossroads

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The old framework is no longer sufficient

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But the new framework has not yet been born

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And the methodology of COGITATE this adversarial collaboration itself

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Perhaps more valuable than any single experimental result

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Because it creates a scientific culture of honesty about failure.

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You can't just do experiments that work for you.

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You have to expose your core projections to the worst possible conditions.

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If this method could be extended to other fields of science

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The reproducibility crisis caused by many low-quality studies may be alleviated

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Which leads me to a deeper question.

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We humans have a deep-rooted cognitive habit

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We like to find that thing.

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What is consciousness?

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Where is it?

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Give me a place

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A mechanism

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It's a switch.

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We love nouns.

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We always turn verbs into nouns.

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Turning sight into vision

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Transforming thinking into thinking

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Turning awareness into consciousness

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But the moment you turn consciousness into consciousness

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You've made a dangerous assumption

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You assume it's a thing

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An entity that can be located, measured, locked in a brain region

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IIT locks it in the posterior cortex, GNWT.

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We shut them up in the prefrontal workspace.

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The results of the experiment found that

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It doesn't stay in any room entirely

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I made a point in the previous video about predictive coding

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Consciousness is not a noun

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It's a verb.

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It's not something you can find.

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It's an ongoing event.

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I told you that your brain is a predictor.

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It creates a controlled illusion about the world all the time

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We then calibrate it with sensory data.

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But the fabrication process itself

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Neither in a single brain region

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It's not a single ignition.

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It's a prediction and calibration loop that the entire brain runs simultaneously on multiple levels.

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The results of this COGITATE experiment

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Instead, it confirms this view from the side

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Consciousness doesn't live in the back, it doesn't live in the front.

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Because consciousness may not be a thing that lives somewhere at all

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It's a whole-brain dynamic.

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Involving posterior sensory encoding

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Classification Integration in the Middle and Attention in the Front

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Continuous exchange of information between regulators

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You single out any link and say it's consciousness

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They all just grabbed the elephant by one leg

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Only Knowledge Sect said something similar two thousand years ago

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Consciousness is not an entity

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It's a process of karmic convergence.

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You go to the brain to find the location of consciousness

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It's like you're looking for the wind in the wind where the wind lives

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The wind doesn't live anywhere

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The wind is the air itself.

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It's not that science has gone wrong.

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Quite the contrary.

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This kind of rollover is a sign that science is approaching the truth

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When your most well-designed models fall apart in the face of your most rigorous experiments

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The crack exposed

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It's a blind spot in the way we ask questions.

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In 1995, Chalmers posed a question that no one has been able to answer.

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It's called the hard problem of consciousness.

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He said you could explain how the brain processes information.

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How do you create behavior? How do you form memories?

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But none of this answers a fundamental question

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Why are these physical processes accompanied by subjective experience?

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Why doesn't everything run in the dark?

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Why is there someone feeling something inside?

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This is a problem that, to this day, no theory has been able to get to the heart of.

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Maybe we don't need a better theory to answer where consciousness is.

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It's about learning to ask a better question.

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After Koch loses the bet in 2023

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Made another bet with Chalmers on the spot

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Bet another 25 years

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He said when I was 91

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Science must be able to understand the neural mechanism of consciousness

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Chalmers is 82 years old

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Shake his hand

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Say yes.

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I'll take it.

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This image particularly moved me

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Two people who have been struggling with consciousness all their lives

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One is the most optimistic neuroscientist.

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One is the sharpest philosopher of consciousness.

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Nobody convinced anybody.

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But no one gave up

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They're still willing to gamble for another 25 years

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It's not because they know the answer.

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It's because they know it's a problem worth a lifetime.

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This reverence for the unknown and obsession with the truth

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That's what impresses me the most about the scientific spirit.

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And maybe that's what consciousness is.

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The more you try to catch it

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The more it slips through your fingers

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It's like you're trying to use a flashlight to illuminate the source of the flashlight itself.

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You can only shine anywhere else

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But the process of you chasing it itself

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It's a process of questioning, rolling over, rebuilding.

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That's exactly what consciousness is doing.

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You think you are searching for consciousness

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But in fact consciousness is the very thing that is being sought.

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What do you think?

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Do you think science will eventually find the switch on consciousness?

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Or is consciousness itself the seeker that can never be found?

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I am Wang Lijie

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See you next time.

